Otitis externa can be categorized into limited otitis externa and diffuse otitis externa. Antibiotics, sedatives and analgesics should be chosen according to the causes and symptoms. 1. Antibiotics: the common causative organisms of limited otitis externa are mainly Staphylococcus aureus and sometimes Staphylococcus albicans; the common causative organisms of diffuse otitis externa are Staphylococcus aureus, Streptococcus haemolyticus, Pseudomonas aeruginosa and Proteus mirabilis, and so on. According to the type of causative organisms, sensitive antibiotic treatment should be selected, such as amoxicillin, cefaclor and so on. 2. Sedative, analgesic: the main symptom of this disease is early earache is intense, aggravated by opening the mouth, chewing, and can be radiated to the same side of the head. Generalized discomfort, body temperature may rise slightly. There is auricular pulling pain and ear screen pressure pain. Those with severe pain need to use non-steroidal anti-inflammatory drugs such as ibuprofen and acetaminophen to provide antipyretic and analgesic effects. Sedatives such as eszopiclene may be used as appropriate. When otitis externa occurs, you need to actively seek medical attention to clarify the cause and extent of the condition, and follow the doctor’s instructions for standardized treatment.