Tuberculous pleurisy taking 3 drugs without adverse effects usually takes 6 to 12 months, special circumstances need to extend the treatment period. Tuberculous pleurisy generally take tuberculosis standard chemotherapy program, currently commonly used short-course therapy, commonly used drugs are isoniazid, rifampicin, ethambutol, pyrazinamide and streptomycin and so on. Short-course therapy is a treatment program that rapidly kills Mycobacterium tuberculosis inside and outside the cells at different reproduction rates in the organism, so that the sputum bacilli can turn negative at an early stage and remain negative for a long time, which has the advantages of rapid dissipation of lesions and fewer long-term recurrences. For first-time patients, if there is no adverse drug reaction or the reaction is mild, after making the medication program under the guidance of professional physicians, it usually takes 2 months of intensive period and 4 months of consolidation period to achieve the above purpose. For patients who have been retreated, their conditions are more complicated, so they should do drug sensitivity test and formulate drug regimen according to the results, and it usually takes 8 to 12 months or more to achieve the above purpose. For patients with drug-resistant tuberculosis, the treatment program should be formulated based on drug sensitivity test and previous drug history, and generally the intensive period for such patients should be 9-12 months, and the total course of treatment should be 20 months or longer, depending on the sputum culture to monitor the effect of treatment. Tuberculosis treatment should strictly follow the principles of early, regular, whole course, proper dosage and combination, otherwise it may also affect the treatment effect as well as the duration of treatment.