Ophthalmospasm mostly refers to the spasm of eyelid muscles, patients may have the symptom of eyelid throbbing, which may be the pathological manifestation caused by ocular inflammation such as conjunctivitis, blepharitis, neuritis, etc., and may also be caused by some physiological factors, such as sleep deprivation and overuse of the eyes. If the patient has long-term sleep deprivation or excessive eye use, because of visual fatigue, the patient may have muscle spasm around the eyes, when this happens, the patient can close the eyes to rest, reduce eye use, and at the same time, use warm towels to improve blood circulation around the eyes, so as to relieve the patient’s symptoms of visual fatigue. Conjunctivitis, keratitis and other ocular inflammatory diseases or facial neuritis, tumor compression of the facial nerve, etc., may lead to patients with eyelid muscle spasm, patients can use anti-inflammatory eye drops under the guidance of the doctor and nutritive nerve medication, such as levofloxacin eye drops, methylcobalamin and so on. In daily life, patients need to avoid staying up late, pay attention to work and rest, and can also be relieved by eye massage to alleviate the symptoms of eye discomfort. It is recommended that patients with frequent blepharospasm should seek prompt medical attention to assess their condition and follow the doctor’s instructions for treatment.