Generally speaking, metformin can play a role in lowering blood sugar by taking one tablet a day, but due to individual differences in patients, the exact number of tablets can achieve satisfactory glucose-lowering effect should be in accordance with the doctor’s instructions. Metformin is a kind of biguanide glucose-lowering drug, commonly used in patients with type II diabetes mellitus whose dietary control is unsatisfactory, especially those who are obese and with hyperinsulinemia. If the use of this drug may appear nausea, diarrhea, vomiting, taste abnormalities and other adverse reactions after, it is recommended to stop the drug in time to seek medical attention. This drug is contraindicated in patients with renal dysfunction and severe infections as well as trauma, hypersensitivity to metformin hydrochloride, acute or chronic metabolic acidosis. Patients are advised to use Metformin under medical supervision and not to use it privately.