Methylcobalamin is an endogenous coenzyme B12, a derivative of vitamin B12, which promotes axonal transport function and axonal regeneration. It is primarily used in the treatment of peripheral neuropathies. Methylcobalamin can be used after the occurrence of rash, loss of appetite, nausea, vomiting, etc.; methylcobalamin allergy patients are prohibited. Methylcobalamin should be discontinued if it is ineffective for more than one month; workers engaged in mercury and its compounds should not take the drug for a long time. Vitamin B1 is involved in the formation of coenzymes in the body and maintains the functions of human sugar and nerve and digestion. This product is mainly used for the prevention and treatment of vitamin B1 deficiencies, such as neuritis, pediculosis, dyspepsia and so on. Vitamin B1 overdose may cause headache, irritability, lack of appetite, swelling of limbs and other symptoms. It is contraindicated in patients who are allergic to vitamin B1. It is contraindicated when there is a change in the properties of the product. Children should be supervised by an adult. If you need to use the above drugs, you should choose the drug treatment under the guidance of the doctor according to the patient’s condition to avoid adverse consequences.