Based on creatinine 700μmol/L alone, it is usually not possible to determine whether the patient has uremia or not. If diabetes mellitus is caused by acute factors that lead to increased creatinine, it is usually not uremia; if diabetes mellitus develops into diabetic nephropathy, which leads to increased creatinine, it is necessary to combine with other related indexes to estimate glomerular filtration rate, and then determine whether it is uremia.
If diabetes mellitus is caused by pre-renal factors such as massive blood loss, diarrhea, renal artery embolism, etc., renal factors such as toxicity caused by drugs or heavy metal ions, etc., and post-renal factors such as bilateral urinary obstruction, etc., after correcting the reversible factors, the renal function may be gradually recovered, and this is not a case of uremia.
If diabetes mellitus progresses to diabetic nephropathy, which leads to elevated creatinine, it is necessary to combine the patient’s urea, cystatin C, gender, age, ethnicity and other information by various formulas to calculate the glomerular filtration rate, and when the glomerular filtration rate is <10 ml/(min-1.73m²), then the diagnosis of uremia can be made.
If diabetic patients have elevated creatinine, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.