Alpha-fetoprotein 50 (μg/L) may be physiologically increased and is usually not important, but serious liver disorders cannot be ruled out. Alpha-fetoprotein is a glycoprotein synthesized mainly in fetal hepatocytes and yolk sacs, while in adults it is replaced by albumin and is present in very small amounts. However, alpha-fetoprotein is elevated to varying degrees in liver and ovarian cancer, pancreatic cancer, malignant teratoma, cirrhosis, hepatitis and other diseases. Normal value of alpha-fetoprotein <25μg/L, pregnant women laboratory alpha-fetoprotein 50μg/L may be due to the fetus newborn tender liver cells secretion of alpha-fetoprotein into the maternal bloodstream, belong to the physiological, generally does not matter. In addition, benign liver diseases such as hepatitis and fatty liver may show a transient mild increase in alpha-fetoprotein, with a positive correlation between the increased value and the degree of necrotic regeneration of hepatocytes. It should be noted that as a serum marker for primary liver cancer, a mild increase in alpha-fetoprotein up to 50 μg/L does not exclude the possibility of early-stage primary liver cancer, and regular review is required to check for a further sustained large increase. This is a serious situation, and should be treated with medical advice.