Mild duodenal deformity can be recovered after active treatment, but moderate to severe duodenal deformity cannot be recovered. Duodenal bulb deformity is caused by duodenal bulbitis, duodenal bulb ulcer, duodenal tumor and other factors of duodenal bulb deformity, duodenal deformity can be recovered with the severity of the disease. If the patient’s condition is mild, after standardized treatment, the general prognosis is good and will not leave sequelae. If the duodenal deformity is serious and even leads to obstruction of the digestive tract, conservative treatment with medication will not be able to make it recover, and the patient will need to undergo surgical treatment to remove a section of the obstructed intestinal tube. Duodenal deformation in the endoscopy can be seen on the mucosa side of the finger-shaped cut, can be shallow with intestinal peristalsis, disappear, the shape of the mountain, petal type and small ball and other deformities. Duodenal ulcer is not standardized treatment, resulting in the formation of duodenal scar is the main cause of deformation, so once diagnosed with duodenal ulcer and other diseases, the patient needs to consult a doctor in a timely manner, follow the doctor’s instructions for standardized treatment, to avoid causing serious sequelae.