Taking medication for tuberculous pleurisy does not usually cause the skin to turn yellow, and it needs to be determined by the length of time the medication is taken and the severity of the disease. Patients need to take anti-tuberculosis drugs for a long time when they develop tuberculous pleurisy. Anti-tuberculosis drugs may cause more serious damage to the patient’s liver, and if taken for a long time will lead to liver damage, resulting in high total bilirubin, which will cause the skin to turn yellow. After the disease is cured, the dosage of the drug will be gradually reduced and the skin changes will gradually improve. Anti-tuberculosis drugs do not usually cause direct skin changes. Anti-tuberculosis drugs need to be used under the guidance of a professional doctor, and during the period of taking the drugs, you need to go to the hospital regularly for liver examinations, if there are any abnormalities, you can change the treatment plan in time, to avoid the burden of drugs on the liver.