Long-term use of escitalopram tablets may cause gastrointestinal reactions, affect the regulation of blood glucose and liver function abnormalities and other adverse reactions, may also appear to turn dry symptoms. 1. Gastrointestinal reaction: nausea and vomiting, dry mouth and bitterness may occur, but also epigastric discomfort or constipation, diarrhea and other symptoms. 2. affect the regulation of blood sugar: for diabetic patients, taking escitalopram tablets may affect the regulation of blood sugar, patients using insulin and hypoglycemic drugs should adjust the dose of the drug. 3. Abnormal liver function: Abnormal liver function may occur, regular testing of liver and kidney function is needed to prevent abnormal liver function. 4. Turning dry: long-term use of escitalopram tablets, to a certain extent, there is a possibility of turning into mania, patients must be carefully observed in the course of taking the drug to prevent manic episodes. It is recommended that patients should go to the hospital for examination in time if the above adverse symptoms occur after taking the drug.