Patients with photophobia, soreness and inability to open their eyes may be caused by dry eye, keratitis, visual fatigue, etc. Patients can alleviate their discomfort by practicing good eye habits and taking medication. 1. Dry eye: Dry eye is usually caused by a combination of factors, and patients may experience symptoms such as dryness, tingling, foreign body sensation, and photophobia. Patients can follow the doctor’s instructions to use artificial tears, such as sodium vitrate eye drops, to lubricate the eye surface, relieve eye discomfort and promote recovery. 2. Keratitis: keratitis caused by pathogenic microbial infections, patients can also appear dry eyes, photophobia and other discomforts, patients can follow the doctor’s instructions to use levofloxacin hydrochloride eye drops, acyclovir eye drops and other medications, to control inflammation, and promote recovery. 3. Visual fatigue: If patients use their eyes excessively, such as watching electronic products for a long time, staying up late for a long time, there can also be sore eyes, photophobia and other discomforts, the patient needs to pay attention to rest, generally reasonable eye use, the patient’s discomfort can be improved, and does not require special treatment. It is recommended that patients who suffer from photophobia, soreness and discomfort should consult a doctor in a timely manner to assess their condition and follow the doctor’s instructions for treatment.