The treatment of diarrhea in infants after receiving the 13-valent pneumococcal polysaccharide conjugate vaccine depends on the specific situation. Mild diarrhea does not require special treatment, while more severe diarrhea requires symptomatic antidiarrheal treatment. After the 13-valent pneumococcal polysaccharide conjugate vaccine for infants, the immune system will have a corresponding immune response, showing temporary immune dysfunction, resulting in a temporary decline in immunity, which will easily lead to the emergence of minor discomfort, such as mild diarrhea, fever, etc., and most of the time it will be relieved in about 2-3 days and does not need to be treated. If the diarrhea symptoms continue to be unrelieved after the 13-valent pneumococcal polysaccharide conjugate vaccine, it is recommended to consult a doctor in time, under the guidance of the doctor to give local hot compresses, massage and adjustments, if necessary, follow the doctor’s instructions orally Montelukast to stop diarrhea, auxiliary bacillus subtilis bacillus granules to regulate the intestinal flora, to help improve the symptoms as soon as possible. It is recommended to strengthen the adjustment of the infant’s supplemental food structure when the infant’s diarrhea, avoid adding indigestible supplemental food, eliminate the adverse factors. The above medication should be used under the guidance of a doctor.