High serum bicarbonate suggests that the body may have metabolic alkalosis or respiratory acidosis. If the serum bicarbonate is high, it is necessary to consult a doctor in time for relevant examination and treatment. 1. Metabolic alkalosis: If excessive use of sodium bicarbonate is used in correcting acidosis, or if too much acid is discharged from the body, such as excessive loss of gastric acid due to severe vomiting or gastrointestinal decompression, etc., the above factors will lead to a relative increase in bicarbonate in the blood. 2. Respiratory acidosis: When the patient has craniocerebral injury, overdose of sedative drugs, which inhibits the respiratory center and causes obstruction of carbon dioxide discharge, which results in carbon dioxide retention in the body, causing an increase in arterial partial pressure of carbon dioxide, and the occurrence of respiratory acidosis, high serum bicarbonate will occur. In normal times, the body’s pH is always in a dynamic state of change. If high serum bicarbonate occurs, consult a doctor for further treatment.