Hepatitis B pregnant women for mother-to-child interruption, should be in pregnancy should adhere to the injection of immunoglobulin, the child was born immediately after the injection of hepatitis B vaccine, and prohibit breastfeeding. 1. During pregnancy: regular monitoring of hepatitis B virus DNA is needed during pregnancy, and if the viral level is high, hepatitis B immunoglobulin should be injected under the guidance of the doctor, which can enhance the immune antibody and achieve the chance of blocking mother-to-child transmission. 2. After the child is born: (1) Immediate injection of hepatitis B vaccine: newborns need to be vaccinated against hepatitis B immediately after birth, usually the first injection is given 24 hours after birth, and one injection is given one month, two months and seven months after birth respectively, which aims to play an immunization role and prevent infection with hepatitis B virus. (2) Prohibition of breastfeeding: Women who are hepatitis B carriers or have hepatitis B virus should be prohibited from breastfeeding because hepatitis B virus can be transmitted through breast milk. If pregnant women have hepatitis B, they should follow the above ways to prevent mother-child blockage, and for pregnant women with serious viral infection, they should also be vaccinated with hepatitis B vaccine during pregnancy, but it should be carried out under the guidance of doctors.