Pancreatic pain often manifests as persistent severe epigastric pain accompanied by abdominal distension, nausea and vomiting. Pancreatic diseases that manifest as abdominal pain are commonly seen in pancreatitis and pancreatic tumors. 1. Pancreatitis: Abdominal pain is the main symptom. Acute cases often have a sudden onset after a full meal or drinking alcohol, while chronic cases last longer. Usually, it is severe abdominal pain in the left upper abdomen, radiating to the left shoulder and lumbar back; patients with biliary origin suffer from right upper abdominal pain at the beginning, gradually transferring to the left side; when the lesion involves the whole peritoneum, the pain range is wider. 2. Pancreatic tumors: such as pancreatic cancer, peripancreatic cancer, etc. Early stage patients often have epigastric pain and discomfort as the first symptom, and a few patients (about 15%) may have no pain; in middle and late stage patients, the abdominal nerve plexus is involved by the cancer, which may result in persistent and severe abdominal pain radiating to the lumbar and back side, which may affect the sleep and diet seriously. If pancreatic pain is suspected, it is necessary to go to the hospital in time to get a clear diagnosis and treatment plan, and use drugs under the guidance of doctors, avoid self-medication.