Children with fever cold hands and feet, seen in the early stages of fever, it is recommended that local warmth, should be appropriate “cover”, and dynamic monitoring of body temperature, as appropriate, the use of ibuprofen and other antipyretic drugs. Fever is a common symptom of pediatrics, due to the baby thermoregulation center is not well developed and their own immunity is weak, vulnerable to pathogens, and the body temperature rises. Peripheral vasoconstriction can occur during the period of rising body temperature, manifested by cold hands and feet, can also be accompanied by pale skin, chills and other phenomena, and some children may have convulsions. It is usually recommended that during this process should be in the extremities of the end of the warm, appropriate “cover”, improve the baby due to chills and cold hands and feet and other discomfort, and dynamic monitoring of body temperature, as appropriate, the use of antipyretic drugs (such as ibuprofen or acetaminophen) to reduce fever. If sweating, warm hands and feet occur, reduce clothing and adjust the room temperature as appropriate. Children with fever and cold hands and feet are recommended to consult a doctor and have a specialist guide the intervention. All the above medications should be used under medical supervision, avoid self-medication.