The treatment drugs for low potassium and high blood pressure include potassium-sparing diuretics, beta-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, etc. It is recommended to use the drugs under the guidance of doctors, and the drug regimens are different in different cases. 1. Potassium-preserving diuretics: spironolactone, amphotericin, can cause hyperkalemia, should not be combined with ACEI, renal insufficiency is prohibited. 2. β-blockers: metoprolol, bisoprolol, atenolol, carvedilol, are suitable for all kinds of hypertension of different severity, especially for middle-aged and young patients with fast heart rate or patients with angina pectoris and chronic heart failure, adverse effects mainly include bradycardia, weakness and cold limbs. When hypertension is combined with hypokalemia, this kind of drug can be applied and potassium chloride tablets can be taken orally to replenish potassium at the same time. 3. Calcium antagonist (CCB): nifedipine extended-release tablets, amlodipine, nifedipine, verapamil, with fast onset of action, strong effect, positive correlation between dosage and therapeutic efficacy, small individual differences in therapeutic efficacy, and other types of antihypertensive drugs used in combination to significantly enhance the effect of lowering blood pressure. Patients with hypotension can take potassium chloride tablets orally at the same time. 4. Angiotensin-converting enzyme inhibitors (ACEI): captopril, enalapril, benazepril, for patients with heart failure, myocardial infarction, diabetic nephropathy with hypertension, with potassium-preserving effect. Adverse reactions: irritating dry cough and angioedema. 5. Angiotensin II receptor antagonist (ARB): Chlorosartan, Valsartan, Irbesartan, for all kinds of mild to moderate hypertension patients, especially ACEI cause intolerable dry cough, this kind of drug also has potassium-preserving effect. Hypokalemia combined with hypertension patients are advised to take regular medication under the guidance of a doctor, and at the same time pay attention to observe the blood pressure and recheck the blood potassium situation, and not blindly take medication on their own.