Occlusion of the right middle cerebral artery with collateral circulation still requires treatment. Right middle cerebral artery occlusion with collateral circulation may have no clinical symptoms, but the main cause of occlusion is atherosclerosis, and medication is needed to prevent stenosis and occlusion of other blood vessels. Commonly used drugs include aspirin and other anti-platelet aggregation, atorvastatin and other plaque stabilizing drugs, and also need to control other related risk factors, such as a light diet, quit smoking and drinking, maintain a good state of mind and adequate sleep. It is recommended that patients seek early medical treatment, and under the guidance of the doctor to carry out the appropriate treatment, do not blindly self-medication.