Patchy baldness has the potential to heal itself. Pemphigus vulgaris is a common dermatologic condition, with the typical symptoms of a round or oval spot of hair loss appearing suddenly on the scalp, with a relatively clear border, no scarring at the site of hair loss, and no other inflammatory reaction. The cause of hair loss may be related to genetics, mental and emotional stress, endocrine disorders, immune inflammation and other multiple factors. Patchy baldness has the possibility of natural healing, and most patients with limited patchy alopecia have the probability of self-healing after active conditioning. However, if the baldness is prolonged and the area affected by the baldness is large, the likelihood of hair regrowth in the area of hair loss will be reduced. Although baldness can heal on its own, it should be treated early in order to prevent the condition from getting worse. Minoxidil application and hormonal creams such as hydrocortisone butyrate cream can be used to apply to the affected area. If the lesions are large in size, oral hormonal drugs such as prednisone can be considered. To summarize, it is recommended that patients with pemphigus vulgaris consult a doctor in time and strictly follow the doctor’s instructions to regulate the treatment. The above drugs should be used in accordance with medical advice.