White mucous membrane inside the mouth may be coccidioidomycosis, lichen planus, oral leukoplakia, need to go to the hospital after examination, follow the doctor’s advice to use metronidazole, prednisone, retinoic acid and other drugs or surgical treatment. 1. Coccidioidomycosis. Oral infection with staphylococcus or streptococcus, in any part of the oral mucosa can appear congested vesicles, covered with yellowish-white or grayish-white pseudomembrane can be wiped away, the treatment needs to be smear examination of the bacterial culture, to determine the pathogenic bacteria, the use of targeted antimicrobial drugs (metronidazole, amoxicillin) treatment. 2. flat moss. Oral lichen planus, can see the oral mucosa with small papules connected to the white or gray-white reticulated pattern, can not be erased, high up the mucosal surface, the treatment of the use of retinoic acid ointment applied locally, oral prednisone and other drugs. 3. Oral white spots. When there is oral white spot, white mucosa can be seen on the oral mucosa, soft to touch, can not be wiped away, mostly asymptomatic, treatment of oral retinoic acid, vitamin E, cancerous tendency of the need for surgical treatment. The white mucous membrane inside the mouth needs to be diagnosed according to the nature of the white mucous membrane, clinical manifestations and laboratory tests to diagnose the cause of the disease, and then targeted medication under the guidance of a physician. Taking the above drugs may cause dry mouth, liver and kidney function damage, pregnant women and children should be used with caution.