Frequent inflammation of tonsils usually does not lead to cancer, but the possibility of repeated stimulation of inflammation or the development of cancer under the action of other pathogenic factors cannot be ruled out. The etiology of tonsil cancer is not well understood, and may be related to excessive smoking and alcohol consumption, frequent betel nut chewing, human papillomavirus infection, and a history of head and neck cancers; immune function deficiencies may increase the risk of developing this disease. In the course of prolonged and often repeated inflammation and repair of the tonsils, the possibility of cancerous transformation exists when stimulated by pathogenic risk factors due to low local resistance. After the appearance of tonsillitis, it is necessary to promptly use antibiotics such as amoxicillin and cefadroxil for anti-infective treatment, and it is also necessary to maintain a light personal diet in order to avoid continued aggravation of the condition and recurrent episodes. When tonsillitis attacks, it is recommended to follow the doctor’s guidance to take timely standardized treatment.