Children with abdominal pain and fever can be seen in the digestive tract diseases (such as acute gastroenteritis, acute appendicitis, etc.) or other systemic febrile diseases, etc., the treatment needs to be decided according to the cause, such as acute appendicitis, if necessary, need to be surgical treatment. 1. Digestive tract diseases: (1) Acute gastroenteritis: can be caused by viral or bacterial infections, clinical symptoms can be fever, abdominal pain, often accompanied by diarrhea, vomiting and so on. These children need to use Saccharomyces boulardii to regulate the intestinal flora, and can also take Sifuotang oral solution to relieve abdominal pain. For children with fever, warm water can be used to reduce the temperature physically, such as wiping, if the temperature exceeds 38.5 ℃ need to use ibuprofen and other drugs to reduce fever. Suspected bacterial infection caused by the need to use antibacterial drugs (such as cefaclor) treatment. (2) Acute appendicitis: It is a common surgical disease of the digestive system, which is often manifested by the above phenomenon, and the abdominal pain can be manifested as periumbilical pain and metastatic right lower abdominal pain, which is atypical in some children. These children need to be actively treated with antibacterial drugs (e.g. cefotaxime, etc.) to fight infection, and surgery is needed if necessary. 2. Other systemic febrile diseases: for example, acute upper respiratory tract infection, fever can occur during the course of the disease, affecting gastrointestinal function, functional abdominal pain symptoms. This kind of children need to actively treat the primary disease, such as suspected bacterial infection need to use cefaclor and other anti-infective treatment, if necessary, the use of antipyretic drugs, such as ibuprofen and other antipyretic and so on. All of the above drugs should be used under the guidance of a physician, and it is recommended to actively consult a specialist to analyze the condition and guide the treatment.