Probiotics can be given to babies for a long time, but they need to be applied under the guidance of a physician. Probiotics (e.g. Bacillus subtilis dictyostelium granules) are used for a variety of gastrointestinal symptoms and related acute and chronic diarrhea and dyspepsia due to intestinal flora disorders; they can also be used for the prevention and treatment of intestinal dysbiosis caused by other reasons (e.g., prolonged use of broad-spectrum antibiotics). After the symptoms are relieved, the drug can usually be stopped, but for some diseases, such as antibiotic-associated diarrhea and other diseases can be long-term oral probiotics to regulate intestinal flora. Probiotics are usually best kept refrigerated, the temperature of the water when brewing probiotics should not exceed 40 ℃, and should not be taken at the same time as antibiotics. Probiotics adverse reactions are not yet clear, contraindications are not yet clear, and some of the probiotics are health products, does not have a therapeutic effect of drugs, parents should pay attention to the purchase, strictly comply with the doctor’s instructions for the use of drugs.