Helicobacter pylori triple therapy includes one proton pump inhibitor, such as omeprazole, etc.; two antibiotics, such as amoxicillin and clindamycin. 1. Proton pump inhibitors: including omeprazole, lansoprazole, rabeprazole, pantoprazole, epprazole, esomeprazole and so on. Such drugs can inhibit gastric acid secretion, which is conducive to antibiotics to play its antibacterial effect. Long-term application can lead to vitamin B12 deficiency. Severe renal insufficiency, infants and young children, pregnant and lactating women are prohibited. 2. Antibiotics: including amoxicillin, clindamycin, metronidazole, tinidazole, levofloxacin, furazolidone, tetracycline and so on. These antibiotics have a powerful bactericidal effect on Helicobacter pylori, and the choice of antibiotics should be based on drug resistance. Note that long-term application requires regular checkups of liver and kidney functions, and should be used with caution in pregnant and lactating women. In recent years, the resistance of H. pylori to antibiotics such as clindamycin has increased, and the eradication rate of classical triple therapy has decreased significantly. Currently, the most effective eradication program recommends quadruple therapy, which is the addition of a bismuth agent to triple therapy. Bismuth agents include bismuth potassium citrate and bismuth pectin. After taking bismuth agent, the tongue and feces often turn black, which is normal and no need to worry. Bismuth is contraindicated in people with poor kidney function. The above drugs should be taken on time and in accordance with the dosage under the guidance of a doctor, avoiding unauthorized use of drugs.