Having hair loss after a leukemia transplant may be a rejection reaction or it may be caused by other diseases. Hematopoietic stem cell transplantation is a fundamental method of treating leukemia at present, and after successful transplantation, some patients will have certain rejection reactions. Common manifestations of rejection include diarrhea, liver function impairment, skin rash, oral mucosal damage, arthritis, cataracts, etc. Symptoms associated with connective tissue diseases can also occur. Hair loss may also be a manifestation of rejection, and generally speaking, after the rejection is effectively controlled, the hair will grow back slowly. In addition, seborrheic alopecia, pemphigus, and other can also cause hair loss. Therefore, when hair loss or other rejection reactions occur after leukemia transplantation, it is recommended to consult a doctor in time to clarify the cause of the disease and receive appropriate treatment after excluding other diseases.