Stomach discomfort when standing upright and relief after lying down are considered to be related to gastric ptosis, chronic gastritis, duodenal ulcer and other causes. 1. Gastric ptosis: Gastric ptosis is caused by insufficient suspension force of the diaphragm, decreased function and laxity of the supporting ligaments of the intra-abdominal organs, decreased intra-abdominal pressure, and low gastric tone, etc. Gastric ptosis is aggravated when standing up and symptoms of gastric discomfort may appear, and gastric discomfort will be relieved when gastric ptosis is relieved after lying down. 2. Chronic gastritis: this disease is mostly related to Helicobacter pylori infection, drugs, toxins, autoimmune, age and other factors, mainly manifested as discomfort in the middle and upper abdomen, fullness, dull pain and so on. When the patient sits or stands upright, gastric acid may stimulate the lesion site, lying down after a change in body position may cause gastric acid to transfer to other locations, the lesion site of the stimulus to reduce the discomfort of the symptoms will be reduced. 3. duodenal ulcer: mainly related to the invasive effect of gastric acid, pepsin and the duodenal mucosal defense ability is out of balance. When standing upright, gastric acid corrodes the ulcer site, which will cause discomfort and pain, and when lying down, the gastric acid covering the ulcer surface may be transferred to other parts of the ulcer, thus reducing the discomfort. It is recommended that the patient go to a regular hospital in time, under the guidance of the doctor according to the specific test results to clarify the cause of the disease, and take targeted treatment.