Vomiting in chronic renal failure is a common symptom of the digestive tract, mainly due to the stimulation of gastrointestinal mucosa by nitrogen metabolites, and the treatment includes: nutritional therapy, symptomatic treatment, and blood purification therapy. 1. Nutritional therapy, control protein intake, reduce the production of nitrogen products. High-quality low-protein-based, such as lean meat, egg white, at the same time, oral keto acid tablets to supplement essential amino acids, to prevent malnutrition. 2. Symptomatic treatment, oral or intramuscular metoclopramide to stop vomiting, oral promotion of gastrointestinal dynamics of drugs, such as domperidone, mosapride, etc.; oral uremic granules, renal failure, such as through the intestinal discharge of toxins. 3. Renal replacement therapy, including hemodialysis, peritoneal dialysis, kidney transplantation, can generally relieve symptoms. The above medications should be used according to the doctor’s prescription, and should not be used without authorization, so as not to aggravate the condition. Vomiting in patients with chronic renal failure is generally a sign of the progress of the disease, and it is recommended to go to regular hospitals for examination and treatment under the guidance of specialists.