Frequent spitting up of newborns is normal if it comes out of the mouth, but abnormal if it comes out of the mouth or nose. If a newborn spits up from the mouth, it may be due to immature gastrointestinal development, feeding posture, etc. This is a normal situation, and can be dealt with by slowing down the feeding speed and adjusting the feeding posture. If the newborn spits up milk from the mouth or nose, frequent and large amount, this is an abnormal situation. It may be caused by abnormal development of the gastrointestinal tract, infections and other factors, such as gastritis, congenital hypertrophic pyloric stenosis, congenital megacolon and other diseases, which is recommended to seek medical attention to identify the cause of the disease and then treated.