There is no fixed dosage for the combined use of dagliflozin and metformin, which needs to be adjusted according to the patient’s blood glucose situation and should be used in strict accordance with the doctor’s instructions. The recommended starting dose of dagliflozin is 5mg once daily, taken in the morning; the starting dose of metformin is usually 500mg twice daily, taken with meals. Diabetic patients who do not get good results from one hypoglycemic agent can choose to take two hypoglycemic agents at the same time, such as the combination of dagliflozin and metformin. The combination of dagliflozin and metformin should be started with a small dose. The recommended starting dose of dagliflozin is 5mg once daily, taken in the morning, without food restriction; the starting dose of metformin is usually 500mg twice daily, or 850mg once daily, taken with meals. If blood sugar control is stable, you can take this dose for a long time. If blood glucose is not effectively controlled, the dose of either hypoglycemic agent can be increased and blood glucose control continued to be monitored. Dagliflozin may have complications such as genitourinary infections, and is contraindicated in patients with severe infections, renal insufficiency, diabetic ketoacidosis, pancreatic insufficiency, and alcoholism. The most common adverse reactions to metformin are nausea, vomiting, diarrhea, abdominal pain, etc. It is contraindicated in patients with severe complications, alcoholism, and severe renal insufficiency. The drug needs to be taken as prescribed by the doctor.