Elevated transaminases may be caused by transient liver impairment, underlying liver disease, etc. Taking one day of liver protection tablets, the level of transaminase reduction varies from person to person and is related to the patient’s condition. In case of transient liver function damage, excessive fatigue and alcohol consumption before the liver function test may lead to high transaminases. At this time, the transaminases will decrease faster after taking liver protection tablets and can return to normal level, suggesting that the patient’s condition has improved. If there is underlying liver disease, such as viral hepatitis, alcoholic hepatitis, etc., how much aminotransferase will be reduced after taking liver protection tablets, should be considered in conjunction with the patient’s condition. Liver protection tablets have the effect of reducing transaminases. It is used for chronic hepatitis and early cirrhosis. Adverse reactions and contraindications are not clear. Note that the drug should be used under the guidance of a doctor, avoid unauthorized use of drugs to avoid adverse effects. If after 3 days of medication, the patient’s transaminases failed to reduce, it is recommended to consult a doctor in a timely manner, improve the relevant examination, clarify the cause of the disease, and carry out targeted treatment under the guidance of the doctor.