Hemodialysis and peritoneal dialysis have their own advantages and disadvantages, and we can’t say which one is better, we need to choose according to the specific conditions of the patients; we can compare them from the principle of dialysis, the applicable people, and the degree of convenience. 1. Principle of dialysis: hemodialysis uses semi-permeable membrane of machine, blood enters extracorporeal circulation through vascular pathway, toxins and water can be discharged out of the body in a short time, which is beneficial for short-term treatment of diseases; peritoneal dialysis uses its own peritoneum, and realizes the exchange of solutes between blood and dialysis solution by filling dialysis solution into the abdominal cavity, which is useful for the protection of residual renal function to a certain extent. 2. Applicable people: hemodialysis has more dialysis modes, basically there is no absolute contraindication, but for the elderly and people with poor heart function, peritoneal dialysis is the first choice in medicine, because peritoneal dialysis, compared to hemodialysis, has a better stability of blood rheology than hemodialysis; and for diabetes mellitus caused by renal failure, due to the high sugar content of peritoneal dialysis fluid, peritoneal dialysis is not generally chosen; 3. Convenience: hemodialysis is implemented in hospitals, and all the operation processes are completed by medical personnel, the time is about 4 hours, and patients do not need to understand too much medical knowledge or operation standards and requirements, but the disadvantage is that they must come to the hospital for treatment; the biggest advantage of peritoneal dialysis is that it can be performed at home, but because it is operated by patients or family members, catheter-related infections are prone to occur. The choice of specific dialysis methods need to be regular hospital visits, consult a professional physician, regular and reasonable treatment to avoid further development of the condition.