Non-invasive trisomy normal chromosome 1 deletions are more severe and may result in miscarriage during pregnancy, and even if born, may have a variety of disorders. Chromosome 1 is the largest of the 23 pairs of human chromosomes, and if a fetal chromosome 1 deletion is detected after a non-invasive test, most fetuses will experience a miscarriage during pregnancy. And even if miscarriage does not occur, after delivery the fetus will show impaired mental development, overall developmental delay, or even multiple malformations. Chromosome deletion is mostly caused by gene mutation, there is no treatment, so once the initial diagnosis can be confirmed by non-invasive, you need to do further examination, if it is indeed a chromosomal abnormality, it is recommended to terminate the pregnancy.