The corner of the mouth acne lymphatic swelling is considered herpes simplex, sporotrichosis, etc., mainly to strengthen the care, medication, physical therapy and other methods to relieve. 1. herpes simplex: this is caused by the herpes simplex virus infection, if the symptoms are not particularly serious, usually do not need special treatment, can be self-healing, it is recommended that appropriate exercise, enhance immunity, if the condition is more serious, you can choose antiviral drugs, such as famciclovir, penciclovir, can be applied locally aciclovir ointment, penciclovir ointment and so on. 2. sporotrichosis: this is caused by sporotrichosis infection, more common is lymphatic type, there will be subcutaneous nodules, and then form ulcers, mainly along the lymphatic vessels centripetal emergence of new nodules, arranged in strings, can be oral potassium iodide solution, itraconazole treatment, but also through physical therapy. Acne at the corner of the mouth, lymphatic swelling has more causes, should be timely consultation, clear cause symptomatic treatment, drugs need to be used under the guidance of a doctor, not private medication.