Foreign body sensation in the throat, chest tightness and bloating may be caused by gastroesophageal reflux disease (GERD), esophageal cancer, pharyngolaryngitis, heart disease and other diseases, which need to be treated under the direction of the doctor, such as general treatment, medication, surgery and other treatments. 1. Gastroesophageal reflux disease (GERD): the head of the bed needs to be elevated 15~20 cm when sleeping, obese people need to reduce weight, and gastric motivation drugs such as domperidone can be used to treat the disease, magnesium alumina carbonate can neutralize the gastric acid, and aluminum thioglycollate can be used to protect the mucosa. 2. Esophageal cancer: for early esophageal cancer with low risk of lymph node metastasis, endoscopic resection can be considered, and radical surgery is also feasible, using chemotherapy drugs such as cisplatin and paclitaxel and radiotherapy. 3. Pharyngolaryngitis: there may be throat discomfort, and a few patients may have reflux esophagitis symptoms such as heartburn and acid reflux, etc. Avoid eating high-fat and high-sugar food, and use acid-suppressing drugs such as omeprazole and gastric stimulants such as domperidone. 4. Heart disease: angina pectoris patients need to take nitroglycerin treatment to reduce the symptoms of angina pectoris, aspirin for anti-platelet aggregation, to prevent thrombosis. Acute heart attack patients need absolute bed rest, good cardiac monitoring, but also through interventional therapy to make the blocked blood vessels reopen. Foreign body sensation in the throat, chest tightness, stomach distension, there may be other reasons, it is recommended to go to the hospital, improve the examination, a clear diagnosis, symptomatic treatment.