Pressing on the bladder while holding in urine may lead to bladder rupture, urine leakage, and infection of the urinary system. 1. Bladder rupture: The normal capacity of the bladder is 300 to 500 milliliters. Because the bladder wall is made up of migratory cells with good ductility, the hardened bladder wall will become very thin when holding urine. If you suffer from urethral stones, urethral stricture, etc., the bladder rupture may be caused by uneven external pressure. 2. Leakage of urine: because holding back urine can lead to damage to the bladder muscles and nerves, leakage of urine may occur when the bladder is pressed, which may lead to urinary incontinence in severe cases. 3. Urinary tract infections: Holding back urine can also lead to urinary tract infections because urine stored in the bladder for a long time can harbor bacteria. Pressure on the bladder while holding back urine can cause further irritation of the bladder. It is recommended that you make it a habit to urinate on time, do not hold your urine, and do not press on your bladder while holding your urine.