Nails horizontal lines depression need to be based on the cause of the symptomatic treatment, common causes include malnutrition, nail fungus, etc., generally use the method of drug treatment. 1. malnutrition: malnutrition such as anemia, lack of vitamins, etc., affecting the function of the nail matrix cells, so that the synthesis of nail plate protein function abnormally, so that the nails appear horizontal lines, depression, loss of luster and other symptoms. Anemia can be oral ferrous sulfate oral solution, ferrous gluconate oral solution, etc., lack of vitamins can be oral multivitamin tablets to regulate. 2. ringworm of the nail: ringworm of the nail is due to the skin ringworm infection caused by the nail lesions, manifested in the nail plate appeared cloudy, thickening, separation, horizontal lines, depression, shedding and other symptoms. The topical application of 5% amorolfine can be used topically, and in severe cases, oral terbinafine, itraconazole and other antifungal drugs can be used to treat the problem. All of the above drugs should be used under the guidance of a doctor, avoid self-medication. There may also be other causes of nail indentation, it is recommended to go to the hospital in a timely manner to improve the examination, to clarify the cause of the disease and then give targeted treatment.