Restricted opening after mandibular nerve block anesthesia is a common complication after mandibular nerve block anesthesia, which can be relieved on its own in mild cases, and nutritive drugs can be used in serious cases. 1. Self-relief: the restriction of opening after mandibular nerve block anesthesia is mainly due to the injection of anesthetics into the internal pterygoid muscle or biting muscle, resulting in the loss of muscle contraction and diastolic function; usually, it can be relieved by itself after the anesthetics have passed, avoiding smoking and drinking alcohol after the operation, eating less spicy and stimulating food, drinking more water, and maintaining a healthy regular life style. 2. Medication: The more serious symptoms can be relieved by taking nerve-nourishing drugs, mainly including methylcobalamin and vitamin B12. Restricted opening after mandibular nerve block anesthesia, it is recommended that early standardized treatment to reduce the adverse effects of the disease.