There are many types of obesity caused by endocrine disorders. Some are due to hormone secretion improperly caused by diseases caused by obesity, such as insulin resistance caused by obesity, hypothyroidism caused by obesity, and glucocorticoids increased obesity, each disease caused by obesity specific treatment is not the same, according to the situation to analyze the specific, specific treatment. Obesity caused by reduced thyroid hormone secretion is generally due to slow metabolism leading to weight gain. It can be corrected by supplementing thyroid hormone and increasing the body’s metabolism under the guidance of a doctor. If the obesity is caused by the increase of glucocorticoid hormone, it is necessary to distinguish the source of glucocorticoid hormone, to find out whether the focal point is adrenal or pituitary, and targeted treatment. If it is insulin resistance that causes obesity, in this case, it is necessary to actively engage in physical exercise, and if appropriate, under the guidance of a doctor to use drugs against insulin resistance. Endocrine disorders of the population, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to reduce weight.