Gastric ulcers caused by H. pylori infection can be treated with a quadruple combination of drugs, i.e., a proton pump inhibitor plus a bismuth agent plus two antibiotics in combination. The etiology of gastric ulcers is complex, and H. pylori infection is the most common cause. For gastric ulcers caused by this etiology, they should be treated with quadruple medication as prescribed by the doctor, such as the combination of omeprazole, bismuth pectin, amoxicillin, and metronidazole, which can generally improve the condition. The patient’s condition is different, the corresponding drug matching program is also different, should follow the doctor’s advice. During the medication period, some of them may have adverse reactions such as dizziness and skin rash, and need to consult the physician in time. It should be noted that Helicobacter pylori is highly contagious. During the period of treatment, you should do a good job of preventing cross-infection to avoid cross-infection.