Hormone shock therapy for epilepsy is a type of drug treatment that involves the application of high doses of glucocorticoids for a short period of time to control the condition. Most of the epilepsy can be controlled after antiepileptic drug treatment, but a small number of patients with various antiepileptic drug treatment programs are not effective, this part of the epilepsy is known as drug-refractory epilepsy, epilepsy hormone shock therapy is mainly for this part of the epileptic patients, a large number of glucocorticoid medication in a short period of time. Because glucocorticoids have a regulatory effect on central neurotransmitters and regulate the release of inhibitory neurotransmitters, epilepsy can be controlled and the condition can be effectively controlled. Although hormonal shock has good therapeutic effect on refractory epilepsy, hormones can have adverse consequences, such as infection, weight gain, and Cushing’s syndrome. It is important to note that this treatment is prohibited for patients with severe mental illness, active peptic ulcers, systemic fungal infections, and severe hypertension. Hormone shock therapy needs to be used under the guidance of a professional doctor, do not use it on your own, as it may lead to serious adverse reactions.