There is no need to stop taking folic acid when progesterone is low, if you check the normal development of the fetus, you need to actively supplement progesterone to protect the fetus treatment. Low progesterone has nothing to do with taking folic acid, so there is no need to stop taking folic acid, you need to check whether the normal development of the fetus, taking progesterone drugs (such as dydrogesterone, progesterone capsules) to supplement progesterone, so as to promote progesterone rise, to play the effect of preservation of the fetus. Eating folic acid can prevent fetal neural tube malformations, taking folic acid will not lead to a decline in maternal progesterone, nor will it lead to a rise in progesterone, progesterone and folic acid have no direct link and conflict. Low progesterone is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or standardized treatment, can not be indiscriminate use of drugs, so as not to cause adverse consequences.