False depression should refer to a normal person who experiences a temporary depressive mood after a certain trigger event, which usually does not exceed 2 weeks and does not meet the diagnostic criteria for depression, with triggering factors including a bad job, family changes, menstrual flow, etc. True depression is generally defined as depression with a history of more than six months in general, and can last 2-4 weeks in acute episodes, mainly caused by genetics, neurobiochemical disorders, hormonal abnormalities in the body, physical illness, and psychosocial factors such as poor marital relationships. Although both true depression and pseudodepression have typical symptoms such as depressed mood, lack of pleasure, and diminished interest, the discomfort of true depression patients exists for a long time and is often accompanied by psychological symptoms and somatic symptoms, which are not present in pseudodepression. The psychological symptoms of true depression include slowed thinking, decreased attention span, negative cognition, suicidal ideation, delayed behavior, and anxiety. The physical symptoms are mainly sleep disturbance, eating disorder, dizziness, headache, palpitations, sexual dysfunction, etc. Usually, the psychological discomfort of pseudodepressed patients can be relieved by themselves without special means of treatment. However, patients with true depression generally cannot achieve self-healing and should go to the hospital for psychological guidance as well as take fluoxetine, sertraline, paroxetine and other medications as prescribed by the doctor for treatment.