Mid-foot pain can be caused by physiological reasons such as over-exertion, or trauma, metatarsal fasciitis, gout and other reasons. 1. Overexertion: some people who walk too much or stand too long may also experience pain in the middle of the foot, but most people can be relieved after resting. 2. Trauma: due to car accidents, chronic fatigue and other causes of foot fractures and surrounding soft tissue injuries, patients may experience pain in the middle of the foot. 3. Metatarsophalangeal fasciitis: due to long-term walking, friction and other causes of chronic aseptic inflammation of the foot, patients may appear in the middle of the foot pain. 4. Gout: mostly seen in the long-term seafood, alcohol consumption of the population, the patient’s body purine metabolites can not be discharged, accumulation in the foot, the patient may appear in the middle of the foot pain. There may be other reasons for the pain in the middle of the foot, it is recommended to go to the hospital in time to improve the examination, clear cause to give targeted treatment.