The differences between potassium gluconate and potassium chloride generally include different treatment modes, different dosage forms and different degrees of illnesses treated. 1. Different treatment modes: although both potassium gluconate and potassium chloride can replenish potassium for the body, and can also treat and correct hypokalemia, potassium gluconate is mainly suitable for patients with reduced blood volume, and will cause reactions to the gastrointestinal tract after taking. Potassium chloride is mainly used to regulate metabolic abnormality, acidity and alkalinity of body fluids and treat hypokalemia by supplementing potassium ions. 2. Different dosage forms: Potassium gluconate is usually available in colorless and transparent liquid formulations or white powder, while potassium chloride is usually available in tablets or injections. 3. Different degree of treatment: Potassium gluconate has good therapeutic effect on patients with general potassium deficiency or hypokalemia, but patients with severe potassium deficiency or severe hypokalemia should use potassium chloride tablets to replenish potassium ions. If necessary, patients should go to regular hospitals for consultation and choose appropriate drugs for treatment under the guidance of doctors.