Cerebral thrombosis is a type of cerebral infarction. Due to the formation of blood clots in the cerebral blood vessels, the local brain tissue becomes insufficiently supplied with blood and further softened and necrotic. Depending on the location of the thrombus formation in the brain, the symptoms are different. Cerebral thrombosis has the highest incidence of stroke, accounting for more than half of all stroke cases, and occurs mostly in middle-aged and elderly people aged 55-65, more in men than women. It mostly develops in the quiet state. Initially, there may be numbness, weakness, dizziness and headache of the limbs, and within 2-3 days, half of the limbs may be lost, aphasia, impaired consciousness, coma, etc., causing death in severe cases.
Normal cerebral angiography
Severe stenosis of the left middle cerebral artery main stem
Intracranial middle cerebral artery stenosis
Etiology of cerebral thrombosis
1. Vascular wall lesions: atherosclerosis (about 70% of patients with cerebrovascular disease have it), arteritis (caused by infections such as tuberculosis, parasitic, septicemia), congenital anomalies (aneurysm, vascular malformation, etc.).
Extended reading: The occurrence of atherosclerosis is associated with vascular endothelial cell damage, excessive lipids, hypertension, and abnormal hemodynamics. The etiology of the development of atherosclerosis is thought to be related to high levels of blood lipids, particularly a substance called low-density lipoprotein-cholesterol (LDL-C). It is also associated with lifestyle, nutritional and genetic factors. For example, eating foods that contain too much fat (fatty meats, fats and oils) and carbohydrates (sugar, starch, etc.); too little physical activity; obesity, having hypertension, diabetes and their family history (parents or/and siblings with the same disease), etc. Some studies have found that atherosclerosis is associated with genetic mutations such as apolipoprotein, a protein related to fat metabolism.
2. Blood component lesions.
(1), increased blood viscosity. Such as hyperlipidemia, hyperglycemia, hyperproteinemia, dehydration, erythrocytosis, leukemia, thrombocytosis, etc.;
2), abnormal coagulation mechanism. Such as thrombocytopenic purpura, hemophilia, application of anticoagulants, diffuse intravascular coagulation, etc. In addition, pregnancy, postpartum, post-surgery and taking contraceptive pills can cause easy coagulation state.
3, hemodynamic changes: such as hypertension (about 55%-75% of non-embolic cerebrovascular disease), hypotension, cardiac dysfunction (heart failure, coronary artery disease, atrial fibrillation, conduction block), etc.
4. Other.
1), the influence of extravascular factors, mainly the large vessels adjacent to the lesion (such as cervical spondylosis, tumors, etc.) compression, affect the blood supply is not complete ;
2), various emboli formed outside the cranium, etc. A history of hypertension before the onset of the disease accounts for 60%-70%. Mechanism of cerebral thrombosis treated by triple oxygen macroautohemotherapy
The biochemical reaction between trioxin and blood causes the decrease of platelet function activity, the enhancement of plasma fibrinolytic activity, the prolongation of prothrombin activation time and the decrease of fibrinogen content to achieve the effect of thrombus dissolution, anti-platelet agglutination and restoration of blood flow rate. Trioxane and hydrogen peroxide can accelerate the circulation of trihydroxy acid, increase basal metabolism, promote the metabolism of carbohydrates and fats, and decompose the fatty substances adhering to the walls of blood vessels, so as to achieve the purpose of restoring the smoothness of blood vessels and increasing the elasticity of blood vessels. In addition, due to the high redox potential of triox, and the killing effect on bacteria, viruses and fungi, also has a good effect on the metabolism of proteins, lipid complexes and cell membranes, and can improve cell metabolism, hemodynamic properties and blood oxygen delivery capacity.
Xiao Ka’s colleague will take her mother-in-law, who suffers from hypertension, for a course of trioxic macroautohemia every year, and she said that although the old family member does not yet have any symptoms of cerebral thrombosis, prevention is better than cure. Extended reading simple small strokes do not directly lead to patient death, but it is a sign of systemic atherosclerosis. In order to reduce the rate of disability and death, active and effective treatment of small strokes is needed. At this stage, it is proposed that.
1. mini-strokes lasting 30 minutes should be considered as ischemic strokes and require close clinical observation.
2. minor strokes lasting more than 1 hour should be treated according to ultra-early diagnosis and thrombolysis of cerebral infarction (the best time for treatment is administered within 6 hours after the onset).
How to prevent cerebral thrombosis in daily life
1.Diet adjustment
According to the dietary principles of multiple varieties, moderate amount and balance, arrange the food of three meals a day and eat more foods that are beneficial to stroke prevention. It is reported that milk, fish, soybeans, tempeh, peanuts, garlic, onions, strawberries, etc. are beneficial to prevent blood clots.
2.Drink enough water
The normal daily water consumption should reach 2000~2500ml, for the old people, it is more important to drink more water, the old people have the characteristics of dense, sticky, aggregation and coagulation in their blood in different degrees, drinking more water is good for lowering blood viscosity and reducing cerebral thrombosis with the characteristics of dense, sticky, aggregation and coagulation, drinking more water is good for lowering viscosity and reducing the risk of cerebral thrombosis.
3.Quit smoking and drinking
To quit smoking and alcohol, limit salt intake, preferably not more than 5 grams per day, while the diet should not be fatty.
4.Combination of work and rest
Brain use should be moderate, do not last too long, under 60 years of age with the brain for an hour, should rest about 10 minutes, more than 60 years of age with the brain for half an hour, should rest 5 ~ 10 minutes, so as not to be too tired and induced stroke.
5.Living a regular life
The elderly should have a regular life, because the physiological regulation and adaptation function of the elderly is reduced, irregular life, easy to make metabolic disorders, and promote the formation of thrombosis.
6, avoid sleeping after meals
Blood gathers in the stomach and intestines after meals to help the blood supply of the digestive organs, while the blood supply of the brain is relatively reduced, while sleeping after meals, blood pressure drops, which can further reduce the blood supply of the brain and slow blood flow, making it easy to form thrombosis. Therefore, it is best to sleep half an hour after meals.
7.Slow change of body position
Cerebral thrombosis often occurs at night, especially at the moment of going to the toilet. Because of the slow blood flow at night, coupled with the change of position when waking up, it is easy to cause the lack of blood supply to the heart and brain, so you must wake up slowly after going to the toilet at night. In fact, usually do housework should also be careful not to change position too quickly, so as not to cause cerebral ischemia.
8, pay attention to weather changes
Older people have a weakened ability to adapt to the weather, too cold and too hot can make the blood viscosity increase, triggering a stroke, therefore, the temperature changes suddenly cold and hot must take appropriate precautions.
9.Control weight
Exercise to consume excess body fat to reduce the risk of stroke by reducing blood lipids.
10, careful use of drugs
The prolonged use of hypnotics, sedatives, antipsychotics, hemostatic drugs, diuretics, antipyretics (such as compound aminopyrine), anti-asthmatic drugs (such as aminophylline), can increase the chance of stroke.