If diagnosed by a professional doctor, and the condition needs to be taken together, Nicorandil and Trimetazidine can be taken together, but need to pay attention to the contraindications of the drug; if the condition is not in line with the applicability of the drug, it can not be taken together. Nicorandil and trimetazidine are both anti-anginal drugs, of which nicorandil can be used for the treatment of coronary heart disease, angina; trimetazidine as an add-on drug for the first-line anti-anginal treatment is poorly controlled or intolerable stable angina. In terms of efficacy, these two drugs do not conflict with each other, in general, if the condition requires can be taken together. However, trimetazidine should not be used as symptomatic treatment for angina attacks, nor in the initial treatment of unstable angina or myocardial infarction, nor in the first few days before or after hospitalization, and should not be used in conjunction with nicorandil if the patient meets these criteria. Occasional side effects such as headache and dizziness, insomnia and tinnitus, gastrointestinal discomfort may be seen with Nicorandil. This drug is contraindicated in people with glaucoma, severe liver and kidney disease, people who are allergic to this drug, and should be used with caution in pregnant women and lactating women. Trimetazidine may cause occasional side effects such as weakness, gastrointestinal discomfort, itchy skin rashes, etc. This drug is contraindicated in patients with severe renal impairment, allergy to this drug, restless leg syndrome, Parkinson’s disease, tremor. If you want to take Nicorandil and Trimetazidine at the same time, you must be instructed by a specialized doctor.