Chronic superficial gastro-sinusitis can be treated with medication (acid-suppressing drugs, gastric mucosal protectants, gastric motility-promoting drugs such as pantoprazole, aluminum thioglycollate, domperidone and so on), and general treatment. 1. Drug treatment: (1) Acid-suppressing drugs: commonly used drugs are ranitidine, pantoprazole, etc. to inhibit gastric acid secretion. (2) Gastric mucosal protective agents: such as aluminum sulfate, magnesium aluminum carbonate chewable tablets to promote gastric mucosal repair. (3) Gastric stimulants: if accompanied by dyspeptic symptoms, domperidone, mosapride, etc. can be given to increase gastrointestinal dynamics. (4) Quadruple therapy: If Helicobacter pylori is infected, quadruple therapy can be given, which means 2 antibiotics + 1 bismuth + 1 proton pump inhibitor. For example, omeprazole, amoxicillin, metronidazole, bismuth potassium citrate and so on. 2. General treatment: Eat easy-to-digest food, eat small amounts of food, prohibit strong tea, coffee, wine and other foods that stimulate the gastric mucosa. Chronic superficial gastro-sinusitis is recommended to consult a doctor in a timely manner, follow the doctor’s instructions to use medication, not self-medication.