Shoulder pain and inability to lift the hand may be related to frozen shoulder, cervical spondylosis, bone fracture and other factors. 1. Frozen shoulder, self-limited aseptic inflammation of the soft tissues around the shoulder joint for unknown reasons, the inflammation leads to localized swelling and pain in the shoulder joint, which affects the lifting function of the arm, and shoulder pain and inability to lift up the hand. 2. Cervical spondylosis: when the disease is in acute aggravation, due to the herniation of cervical intervertebral discs compressing the nerve roots of the upper limbs, under the influence of cold, acute injury or other unfavorable factors, leading to the aggravation of cervical spondylosis symptoms, there will be a sudden and severe pain in the shoulder joints, and the upper limbs can not be lifted up. 3. Fracture: Fracture can be caused by external force, resulting in shoulder joint fracture and dislocation, which will cause severe pain in the shoulder joint and dysfunction of the upper limb, and shoulder pain and inability to lift up the arm. When you can’t lift your arm with shoulder pain, it is recommended to consult a doctor in time, follow the doctor’s instructions for further examination, and choose a reasonable treatment plan under the doctor’s comprehensive analysis.