The stinging pain in the urethra when urinating is called dysuria, which is caused by urinary tract infection and needs to be treated with antibiotics, such as azithromycin; urethral stones need to be drained and removed for treatment; and urethral stenosis needs to be caused by urethral dilatation. 1. Urethral infection: Urethral infection is the most common cause of urinary pain in men, in this case, after clarifying the causative microorganisms, medication can be carried out, such as azithromycin, levofloxacin tablets, cefixime tablets and so on. All of the above drugs should be applied under the guidance of a doctor. 2. Urethral calculi: Urethral calculi can also cause urinary irritation. Smaller calculi can be washed out by drinking more water. If the stones are large, surgery is recommended. 3. Urethral stenosis: male urethral stenosis can also cause painful urination, this situation needs to go to the hospital on time for urethral dilatation surgery. Overall, after the symptoms of painful urination, you need to go to the hospital in time for examination, to clarify the cause of the disease, and then under the guidance of the doctor for treatment.