When the patient has chills all over the body, it may be related to non-pathological factors such as too little clothing and low temperature of the environment, or it may be related to pathological factors such as infections and iron-deficiency anemia, etc. The patient can alleviate the condition by adding more clothes and medication. 1. Non-pathological factors: when the patient is too thinly dressed, or the temperature of the patient is low, it may cause the symptoms of generalized chills, and the patient should add clothes in time, pay attention to body warmth, and stay away from the cold environment. 2. Pathological factors (1) Fever: when the patient’s body is infected and causes fever, generalized chills may occur. When the patient is caused by bacterial infection fever, you can follow the doctor’s instructions to use amoxicillin, erythromycin, ceftriaxone, clindamycin, ampicillin and other antibiotics for treatment, for viral infections you can use acyclovir, oseltamivir, ribavirin and other antiviral drugs for treatment, the patient has a higher temperature of fever, you can take ibuprofen, acetaminophen for antipyretic treatment. (2) Iron deficiency anemia: when patients suffer from severe iron deficiency anemia, it may also cause generalized chills. For patients with severe anemia, blood transfusion can be carried out, and patients can also take drugs such as ferrous sulfate, iron dextrose, ferrous gluconate, iron sorbitol, etc. under the guidance of the doctor to treat and alleviate the condition. It is recommended that patients strictly follow the doctor’s instructions for medication, actively cooperate with the doctor’s treatment, pay attention to rest in life, strengthen the nutrition, appropriate exercise, if necessary, can go to the hospital in a timely manner.